public beta · research use only

EVIDENCE. IN THE OPEN.

An open hub for AI-generated peptide candidates. Every sequence gets a card. Every card ships with a recipe. Every fork is traceable.

cards 1739
targets 64
authors 1
reproduced 223

PeptideModel is an open research database for AI-generated peptide candidates. Every entry follows a five-level evidence pipeline — designed, computed, reproduced, synthesized, and bioassayed — that distinguishes AI proposals from experimentally validated sequences. Each card records the full prediction recipe (model, version, hardware, seeds, command) for independent reproducibility. All data is CC-BY-SA 4.0 and accessible via a free public API at api.peptidemodel.com. The platform currently indexes 1739 sequences across 64 biological targets.

Semaglutide FLAGSHIP weight loss & type-2 diabetes BPC-157 FLAGSHIP gut healing & tissue repair DF-3 ADVANCED muscle growth GIP (1-30) FLAGSHIP insulin release, obesity treatment Melanotan I FLAGSHIP skin darkening & sun-pain protection Tirzepatide ADVANCED weight loss & type-2 diabetes Retatrutide FLAGSHIP weight loss & metabolism Elamipretide FLAGSHIP stabilizes cellular energy production Oxytocin ADVANCED labor & social bonding TB-500 FLAGSHIP tissue repair & angiogenesis Setmelanotide ADVANCED genetic obesity treatment Sermorelin ADVANCED stimulates growth hormone release Cagrilintide NEWS appetite suppression & weight loss LL-37 ADVANCED kills bacteria & pathogens MOTS-c ADVANCED energy metabolism & longevity Vasopressin ADVANCED water retention & blood pressure Semaglutide FLAGSHIP weight loss & type-2 diabetes BPC-157 FLAGSHIP gut healing & tissue repair DF-3 ADVANCED muscle growth GIP (1-30) FLAGSHIP insulin release, obesity treatment Melanotan I FLAGSHIP skin darkening & sun-pain protection Tirzepatide ADVANCED weight loss & type-2 diabetes Retatrutide FLAGSHIP weight loss & metabolism Elamipretide FLAGSHIP stabilizes cellular energy production Oxytocin ADVANCED labor & social bonding TB-500 FLAGSHIP tissue repair & angiogenesis Setmelanotide ADVANCED genetic obesity treatment Sermorelin ADVANCED stimulates growth hormone release Cagrilintide NEWS appetite suppression & weight loss LL-37 ADVANCED kills bacteria & pathogens MOTS-c ADVANCED energy metabolism & longevity Vasopressin ADVANCED water retention & blood pressure

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GLP-1 tripled natural pregnancies in PCOS. It did nothing for IVF.
The first meta-analysis pooling randomized trials, published October 15 in the European Journal of Obstetrics and Gynecology and Reproductive Biology, compared GLP-1 drugs against metformin in 252 women with polycystic ovary syndrome. Natural conception roughly tripled (OR 3.10, 95% CI 1.74-5.49), but overall pregnancy was not significant (OR 1.41) and IVF showed nothing (OR 1.01). No trial reported live births.
GLP-1R
Half of GLP-1 users get gut symptoms. Most tested stomachs empty normally.
A Mayo Clinic study of 78,277 GLP-1 users, published this month in Neurogastroenterology and Motility, found 53 percent reported a gastrointestinal symptom within five years, led by abdominal pain (28 percent) and nausea (25 percent), with women at higher risk (HR 1.4). But among 696 symptomatic patients sent for a gastric-emptying scan, only 34.6 percent actually had delayed emptying, decoupling the symptoms from the slow-stomach mechanism everyone blames.
GLP-1RGIPR
Icotrokinra eased psoriatic-arthritis joints at week 16. The patients self-reported the arthritis.
A post-hoc pooled analysis of three Phase 3 trials found J&J's oral psoriasis peptide icotrokinra roughly quadrupled the share of patients reporting their joint-disease activity had halved by week 16. Every joint number came from patients who diagnosed their own psoriatic arthritis and rated their own symptoms.
IMMUNE

browse by target · 53 targets indexed

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The grid of family cards becomes a body-map on-ramp. Pick a system — by tab, by the figure, or by the index — and the panel resolves to that region's targets, ranked by activity, one click from the full list.

view anterior · male · icon-led systems · mapped rig

how it works · platform pipeline · all cards

read the protocol →
1designed
1,739100.0%
2computed
1,71298.4%
3reproduced
42224.3%
4synthesized
42124.2%
5bioassayed
25414.6%

Every card carries a five-level status. Anyone can design; computation and reproduction require a recipe and attached artifacts; synthesis requires an LC-MS spectrum; assay requires a protocol and raw data. The funnel is steep because the schema is strict — and that's the point.

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